Treat biological databases as infrastructure, not projects

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  • CORRESPONDENCE

By

  • Katja Röper1,
  • Valerie Wood2 &
  • …
  • Paul Nurse3
  1. Neil Hall
    1. Earlham Institute and ELIXIR-UK, Norwich, UK.

  2. Katja Röper
    1. University of Cambridge, Cambridge, UK.

  3. Valerie Wood
    1. University of Cambridge, Cambridge, UK.

  4. Paul Nurse
    1. Royal Society, London, UK.

Many modern biology studies rely on curated databases that scientists hardly notice until they are gone. PomBase, the knowledge hub for the yeast Schizosaccharomyces pombe, has lost its long-term support from UK funder Wellcome. Another knowledge portal, FlyBase — for research on Drosophila fruit flies — lost funding for its curation team when awards from the US National Institutes of Health (NIH) were cut in 2025. And after a funding gap, the human gene-nomenclature database HGNC secured one NIH award in 2024.

Nature 656, 786 (2026)

doi: https://doi.org/10.1038/d41586-026-02575-5

Competing Interests

The authors declare no competing interests.

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