Retraction Note: Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells

Nature作者:Simona Daniele2026年8月12日正文已收录本站
  • Retraction Note
  • Open access
  • Published:
  • Barbara Costa1,
  • Elisa Zappelli1,
  • Eleonora Da Pozzo1,
  • Simona Sestito1,
  • Giulia Nesi1,
  • Pietro Campiglia2,
  • Luciana Marinelli3,
  • Ettore Novellino3,
  • Simona Rapposelli1 &
  • …
  • Claudia Martini1 

Scientific Reports volume 16, Article number: 25103 (2026) Cite this article

Retraction of: Scientific Reports https://doi.org/10.1038/srep09956, published online 21 April 2015

The Editors have retracted this Article.

After publication, concerns were raised about Figure 7a. An editorial investigation determined that there appears to be an overlap between the two middle control group panels, as well as overlap in the ISA27 panels. The Authors provided some data on request, but the Editors were not able to verify it. The Authors explanation for this overlap was also insufficient. The Editors have therefore lost confidence in this Article.

Simona Daniele, Barbara Costa, Eleonora Da Pozzo, Pietro Campiglia, Simona Rapposelli and Claudia Martini agree with this retraction.

Elisa Zappelli, Simona Sestito, Giulia Nesi, Luciana Marinelli and Ettore Novellino did not respond to correspondence from the Editors about this retraction.

Author information

Authors and Affiliations

  1. Department of Pharmacy, University of Pisa, Pisa, Italy

    Simona Daniele, Barbara Costa, Elisa Zappelli, Eleonora Da Pozzo, Simona Sestito, Giulia Nesi, Simona Rapposelli & Claudia Martini

  2. Department of Pharmacy, University of Salerno, Fisciano, Italy

    Pietro Campiglia

  3. Department of Pharmacy, University of Naples Federico II, Naples, Italy

    Luciana Marinelli & Ettore Novellino

Authors

  1. Simona Daniele
  2. Barbara Costa
  3. Elisa Zappelli
  4. Eleonora Da Pozzo
  5. Simona Sestito
  6. Giulia Nesi
  7. Pietro Campiglia
  8. Luciana Marinelli
  9. Ettore Novellino
  10. Simona Rapposelli
  11. Claudia Martini

Corresponding authors

Correspondence to Barbara Costa or Simona Rapposelli.

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Daniele, S., Costa, B., Zappelli, E. et al. Retraction Note: Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells. Sci Rep 16, 25103 (2026). https://doi.org/10.1038/s41598-026-66458-5

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  • DOI: https://doi.org/10.1038/s41598-026-66458-5