Cognitive resilience helps to predict Alzheimer’s dementia

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The trait could explain why symptoms vary in severity between people with similar brain pathology.

A CT scan of a patient’s brain with Alzheimer's disease, showing internal structures in blue, purple and yellow colours against a black background

A scan shows atrophy in the brain (artificially coloured) of a person with Alzheimer’s disease. Credit: Zephyr/SPL

Researchers have identified a measure of ‘cognitive resilience’ that can account for some of the striking differences in dementia risk seen in people with similar levels of Alzheimer’s pathology1.

doi: https://doi.org/10.1038/d41586-026-02897-4

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