科技科学

Nasal vaccines could stop pandemics before they begin

Nature正文已收录本站
  • OUTLOOK

Sparking an immune response where microbes enter the body should not only stop a person getting sick, but also prevent them spreading the infection to others.

By

  1. Anthony King

    1. Anthony King is a science writer in Dublin.

Vaccines created at the height of the COVID-19 pandemic prevented millions of deaths, especially among older people. But they fell short in stopping the spread of the virus.

Nature 657, S8-S9 (2026)

doi: https://doi.org/10.1038/d41586-026-02656-5

This article is part of Nature Outlook: Drug delivery, a supplement produced with financial support from Taiho Oncology, Inc. Nature maintains full independence in all editorial decisions related to the content. About this content.

References

  1. Mitsi, E. et al. Nature Commun. 14, 6815 (2023).

    Article  PubMed  Google Scholar 

  2. Stacey, H. D. et al. Sci. Transl. Med. 18, eadz8439 (2026).

    Article  PubMed  Google Scholar 

  3. Nguyen, T. D. et al. Nature Commun. 16, 2871 (2025).

    Article  PubMed  Google Scholar 

  4. Li, J. et al. Lancet Infect. Dis. 23, 1143–1152 (2023).

    Article  PubMed  Google Scholar 

  5. Singh, C. et al. npj Vaccines 8, 125 (2023).

    Article  PubMed  Google Scholar 

  6. Gbesemete, D. et al. Lancet Microbe 6, 101211 (2025).

    Article  PubMed  Google Scholar 

Download references

  • A good drug is useless if it misses its target

  • These six advances could change how drugs are delivered

  • Drug-delivering particles aim to breach the blood–brain barrier

  • Special delivery: bacterial couriers are smuggling drugs into cancers

  • Medicines do no good if people don’t take them

  • Drug delivery gets subcellular

  • Dose once, treat forever: drugs are being engineered to last much longer

  • Bacteria recruited to treat cancer

  • Partner content: Patient-centric drug delivery from Tahio Oncology: What does the future hold?

Subjects

Latest on:

  • Vaccines
  • Immunology
  • Public health

  • Does the shingles vaccine cut heart-disease risk? Mounting evidence suggests a link

    News

  • Systems vaccinology and the architecture of human immunity

    Review Article

  • Moderna cancer vaccine stops melanoma returning: what’s next for personalized treatments?

    News

  • Revealed: inside the US military’s plan to tap huge sums from the NIH

    News

  • Immune therapy engineered inside the body eases multiple sclerosis

    News

  • When do infections lead to long COVID? Scientists close in on triggers and treatments for post-viral syndromes

    News Feature

  • A data leak shut a top research biobank: lessons from the recovery

    News Feature

  • Scale of snakebites estimated globally

    News & Views

  • AI models are being used to track zoonotic diseases. Will they prevent the next pandemic?

    Technology Feature