科技科学

Highly efficient base editing at <i>PCSK9</i> and normal human embryo development

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  • Nathan Treff

    Present address: Nucleus Genomics, Inc., New York, NY, USA

  • Columbia University, Department of Pediatrics, Division of Molecular Genetics, New York,, NY, USA

    Stepan Jerabek, Qiaojin Zhao, Julie Sung, Ning Wang, Euihyun Kim, Jimin Kim, Sakshi Bhatele, Melisa Isado, Shuangyi Xu & Dieter Egli

  • Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague 6, Czech Republic

    Stepan Jerabek, Michal Dolezal & Iva Pichova

  • Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea

    Chanju Jung & Sangsu Bae

  • Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Columbia University, New York,, NY, USA

    Michelle Kappy, Robert Prosser & Dieter Egli

  • Institute of Molecular Genetics of the Czech Academy of Sciences, Prague 4, Czech Republic

    Marcos Iuri Roos Kulmann

  • Department of Cell Biology, Charles University, Prague 2, Czech Republic

    Marcos Iuri Roos Kulmann

  • School of Molecular Sciences, Arizona State University, Tempe, AZ, USA

    Madeleine Bliss King

  • Gavin Herbert Eye Institute, Brunson Center for Translational Vision Research, Department of Ophthalmology & Visual Sciences, University of California Irvine, School of Medicine, Irvine, CA, USA

    Madeleine Bliss King, Mitchell John McAndrew & Audrone Lapinaite

  • Department of Medicine, Columbia University, New York,, NY, USA

    Meng Li

  • Department of Life Sciences, Korea University, Seoul, Republic of Korea

    Hong-Su Jang

  • Center for Biomolecular and Cellular Structure, Institute for Basic Science, Daejeon, Republic of Korea

    Hong-Su Jang & Jae-Sung Woo

  • Medical Research Center of Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea

    Gue-Ho Hwang & Sangsu Bae

  • Genomic Prediction, Inc., Hackettstown, NJ, USA

    Jia Xu, Diego Marin & Nathan Treff

  • Department of Genetics, Rutgers University, Piscataway, NJ, USA

    Diego Marin

  • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea

    Sangsu Bae

  • Department of Obstetrics, Gynecology, and Reproductive Sciences, Rutgers University, New Brunswick, NJ, USA

    Nathan Treff

  • Department of Biomedical Engineering, University of California Irvine, Samueli School of Engineering, Irvine, CA, USA

    Audrone Lapinaite

  • Department of Biological Chemistry, University of California Irvine, School of Medicine, Irvine, CA, USA

    Audrone Lapinaite

  • Columbia Stem Cell Initiative, Columbia University, New York, NY, USA

    Dieter Egli