Asthma in some boys stops at puberty: mouse results hint at why

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Study suggests that male hormones have an effect on nerve endings in the lungs.

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A white laboratory mouse explores a bright blue testing platform with several circular holes

Male mice that had their testes removed — or their male-hormone receptors in the lungs turned off – had a heightened response to an inflammatory agent. Credit: Paul Chinn/The San Francisco Chronicle/Getty

Some male hormones could help nerve cells in the lungs to suppress asthma attacks.

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doi: https://doi.org/10.1038/d41586-026-02611-4

References

  1. Tu, X., Chen, H., Ma, X., Donovan, C. & Yang, J. Sci. Immunol. https://doi.org/10.1126/sciimmunol.aed0186 (2026).

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